About Nervexa™

Ending Chronic Joint Pain Without Surgery

Featured In:

The Revolutionary Alternative
to Joint Replacement

Nervexa™ is a minimally invasive, multi-layered approach to chronic joint pain. By targeting nerves, inflammation, and how your brain perceives pain, it provides long-lasting relief, restores mobility, and preserves your natural joint, all without major surgery.

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Our Mission

Making Lasting Joint Pain Relief Accessible to Everyone

We understand how chronic joint pain can affect every part of your life, your mobility, your independence, and even your joy in everyday moments. That’s why our mission is to make advanced, effective treatment accessible to all patients.

Our Nervexa™ approach doesn’t just mask pain, but targets the root causes so you can find permanent relief.

If you’ve been struggling with persistent joint pain, whether from arthritis, injury, or even after a joint replacement, you don’t have to accept it as your new normal. Nervexa™ offers a modern, multi-layered approach designed to restore comfort, function, and confidence in your daily life.

"For too long, patients have been told their only options are temporary injections or a major joint replacement. I created Nervexa™ because I believe there is a better way. By combining advanced nerve science with minimally invasive techniques, we can 'silence' chronic pain at its source."

-Joshua Hustedt, MD, MHS

About the Procedure

How Does Nervexa™ Work?

A 3-step, multi-layered approach to relieve chronic joint pain while
preserving your natural joint function.

Calm Joint Inflammation

Excess blood flow can fuel chronic knee pain. Nervexa™’s targeted musculoskeletal embolization reduces this inflammation, cooling the joint and setting the stage for lasting relief.

Reroute Pain Signals

Through knee denervation, we identify and redirect the nerves sending pain signals. This “silences” the pain permanently while keeping your joint strong and functional.

Long-Term Pain Protection

A small, FDA-cleared device delivers gentle electromagnetic pulses to block any lingering pain signals. Controlled by your smartphone, it acts as a digital safety net for lasting comfort.

Why Choose Nervexa™
To Treat Chronic Joint Pain?

It's minimally invasive

Small incisions, less tissue disruption, and a focused approach mean faster recovery than traditional joint surgery.

It’s medically studied 

Many patients experience lasting relief from chronic joint pain after Nervexa™, even when other treatments haven’t worked.

It’s long-lasting 

Targeted nerve denervation rewires pain signals for long-term comfort, helping you stay active and functional.

It’s fast 

The full treatment can be completed in a quick as a week, with most patients returning to normal activities within six weeks.

Success Rate

in "Clinically
significant" pain relief

Pain Reduction

From Severe (8.7/10)
to Mild (2.9/10)

Improved Mobility

Significant restoration
of physical function.

Increase in Quality of Life

Measured improvement in
daily well-being.

Nervexa™ Medical Studies

Extensively Studied,
Consistent Results

Nervexa™ procedures are backed by rigorous clinical research and real-world evidence, demonstrating safety, effectiveness, and long-term pain relief for patients with chronic joint pain.

Live Life Free From Joint Pain with Nervexa™

“I can walk straighter and bend my knee without feeling like my knee is on fire, which I haven’t had in a long time.”

“There is hope… I’m doing great. I couldn’t even kneel at church before, and now I’m pain-free.”

“The recovery was very quick… I’ve had no issues for three years… I’d rather do this than a full knee replacement.”

Our Team

Meet Your Partners in Advanced Joint Pain Care

Dr. Joshua Hustedt

Inventor of Nervexa™, Award-Winning
Orthopedic Surgeon

Dr. Hustedt is double board-certified in orthopedic surgery and peripheral nerve surgery. He is internationally recognized for his expertise in minimally invasive procedures and nerve-focused treatments for chronic musculoskeletal pain.

The Nervexa™ treatment approach is built on groundbreaking research led by Dr. Joshua Hustedt while at the University of Arizona. Over years of dedicated clinical research, Dr. Hustedt developed and refined these advanced nerve-based techniques and proved their safety and effectiveness through rigorous clinical trials across multiple joints and patient populations.

Education

Dr. Hustedt's clinical foundation was built at the world’s most prestigious institutions:
Yale University: Earned both his Medical Degree and Master of Health Science.
Duke University: Completed advanced surgical fellowship training in Hand, Upper Extremity, and Microvascular.  
Stanford University: Finished BA Human Biology with a concentration in International Health and Development. Academic and athletic standout, setting the stage for a career of high-performance medicine.

Affiliations

Founder: Established the Joint Denervation Consortium and the Knee Treatment Research Group, leading the national conversation on surgery-free pain solutions.
Academic Authority: Served as Clinical Professor and Research Director at the University of Arizona College of Medicine, where he mentored the next generation of surgeons.
Award-Winning Researcher: Internationally recognized for his work in minimally invasive nerve treatments, receiving top honors for his contributions to musculoskeletal science. Over 50 publications in renowned medical journals.

Briana Silvestri PA

Research Associate

Briana is a research associate at the Knee Treatment Research Group (KTRG), specializing in the study and advancement of treatments for knee-related disorders.

With a strong background in biomechanics, sports medicine, and orthopedics, Briana plays a central role in designing and conducting cutting-edge research aimed at improving knee care, rehabilitation, and patient outcomes.